When a defeated Kian finds himself in a dark place, will Jac be able to pull him back from the edge? Meanwhile, a past acquaintance puts Max in a compromising position.

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Jac and Kian return to work, but can they support each other and conquer their demons? Demoted and back in the trenches, Serena must find a role for herself. And will Sacha's efforts to help with Essie's home life only push her into Ben's arms for good?

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It's the day of Sacha's groundbreaking transplant operation. As he is still overcoming a bereavement, Max wonders whether Sacha is fit to carry out the procedure.

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It's Valentine's Day, but will Cupid's arrow hit the target for Chloe and Cameron? Will Nicky risk a life to pay off a debt? A troubled Sacha is guided by the faith of an old friend.

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A reconciliation between Chloe and Cameron seems unlikely after the previous night's events, but nevertheless, he decides to make a bold move to win back her trust. A familiar face returns to Holby to perform surgery on Carole, and Dominic finds a much-needed source of moral support as he waits for the outcome. Jac makes plans for her first unsupervised visit from Emma, but things soon get out of control.

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Ric is determined to do anything he can to help the relative of a former patient, despite the AAU being filled to capacity and the hospital being in the midst of a nursing crisis. Essie realises that he has to decide where he stands with Sasha when Ben makes a grand gesture. Kian returns from Holby from Canada to discover that Jac has been taking a step back from her work, and resolves to force her out of her comfort zone.

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Max finds herself in a desolate state after receiving blind-siding news, Max tasks Jac and Kian to decide who should be Clinical Lead, but neither are quite ready to take on the baton, and a loved up Essie attempts to do the right thing, but her joy is short lived when shocking revelations threaten her friendship with Dom.

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A hectic day sees Cameron seize his chance to impress. Reeling from recent revelations, Sacha, Essie, Dom and Ben face a life-saving surgery with a vulnerable child, and stressed by budget cuts, staffing shortages and an inflexible Max, worried Fletch begins to panic that Holby is heading for disaster.

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Xavier is piecing together the puzzle of Evan's death and getting dangerously close to exposing the truth, Essie thinks the worst thing that will happen to her today is dealing with Children's Services, and Jac is keen to impress the Board with a complex and rare surgery that will put them ahead of the competition.

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Guy Self returns to Holby, and is now in a relationship with a former patient, a development he wishes to keep a secret from a suspicious Ric. Essie begins her second round of chemotherapy, and her friends are determined to make sure that every other aspect of her life remain as normal as possible. Max makes an announcement regarding the future of Darwin, sending Jac and Kian's relationship into new territory.

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Essie attempts to act as if there is nothing to worry about as she starts chemotherapy, but confides in Fletch that she knows they will both face difficult decisions in the future. Guy's past is dredged up, but gets the chance to prove he is better than his reputation - if he can convince Ric to let him operate. Jac is determined to secure a bright future for Darwin after losing a profitable contract, but fears her feelings for Kian may be a distraction.

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Kian struggles to cope as a patient dredges up the past, threatening his relationship with Jac, who has uncovered something suspicious concerning Kestrel. Louis works with Guy on a case, only to fall out when he discovers he has been the subject of hospital gossip. Fletch awaits a confirmed date for his operation, only to cause chaos when he makes a false assumption concerning a garish gift.

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Fletch's surgery is derailed when Evie reveals a secret that makes him question himself, but both suspect they are just making excuses out of a fear of what the future may hold. Nicky treats a familiar face, and is put in a difficult position by her mother that forces her to choose between cutting her off or making a promise she cannot keep. Max's big day is ruined by devastating revelations from three of her colleagues.

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Cameron is devastated after a bad performance review. He is tempted to cross an ethical line to turn things around, but is unprepared for the terrible consequences of his actions. Nicky tries to find a life-saving treatment for Brenda, which puts him at odds with Jac and forced to choose between her professional and personal priorities. Fletch recovers from surgery, and Essie hides the pain from recent events involving Isla.

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